Intedanib Impurity 10
N-Methyl-4-nitroaniline
CAS: 100-15-2
Molecular Formula: C7H8N2O2
Intedanib Impurity 10 - Names and Identifiers
| Name | N-Methyl-4-nitroaniline |
| Synonyms | Nitronaniline Methyl-4-nitroaniline Intedanib Impurity 10 4-nitro-n-methylaniline N-Methyl-4-nitroaniline N-Methyl-p-nitroaniline 4-nitro-N-methylaniline N1-methyl-4-nitroaniline 4-METHYLAMINONITROBENZENE 1-METHYLAMINO-4-NITROBENZENE p-(methylamino)nitrobenzene N-monomethyl-p-nitroaniline |
| CAS | 100-15-2 |
| EINECS | 202-823-2 |
| InChI | InChI=1/C7H8N2O2/c1-8-6-2-4-7(5-3-6)9(10)11/h2-5,8H,1H3 |
| InChIKey | XIFJZJPMHNUGRA-UHFFFAOYSA-N |
Intedanib Impurity 10 - Physico-chemical Properties
| Molecular Formula | C7H8N2O2 |
| Molar Mass | 152.15 |
| Density | 1.2010 |
| Melting Point | 149-151°C(lit.) |
| Boling Point | 294.61°C (rough estimate) |
| Flash Point | 129.5°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.00205mmHg at 25°C |
| Vapor Density | 5.25 (vs air) |
| Appearance | Solid |
| Color | Yellow to Very Dark Yellow |
| BRN | 637920 |
| pKa | 0.56±0.12(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Refractive Index | 1.6276 (estimate) |
| Physical and Chemical Properties | Brown yellow prismatic crystals with violet light. Melting point 152 °c. Soluble in acetone, benzene, ethanol-soluble, insoluble in water. |
| Use | Used as a dye intermediate |
Intedanib Impurity 10 - Risk and Safety
| Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R33 - Danger of cumulative effects R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | 2811 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29214200 |
| Hazard Note | Highly Toxic/Irritant |
| Hazard Class | 6.1 |
| Packing Group | III |
Intedanib Impurity 10 - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| uses | for organic synthesis, dye intermediates. used as dye intermediate |
| production method | is prepared from p-nitroacetanilide, methyl iodide and ethanol as raw materials. Acetone, P-nitroacetanilide and potassium hydroxide were mixed, followed by heating and refluxing, and an acetone solution of methyl iodide was added dropwise. After addition, refluxing was continued for 4 hours. After standing overnight, the acetone was recovered, and crystals were precipitated. After cooling, the alkali was washed off and washed with ethanol to obtain N-methyl-p-nitroacetanilide. Then it was mixed with ethanol and hydrochloric acid, heated and refluxed for 8H to recover ethyl acetate and ethanol, washed with water, washed with acid, and dried to obtain crude product. The crude product is dissolved with acetone, filtered, and the recovered acetone is precipitated to be the finished product. |
Last Update：2024-04-09 19:55:45
Supplier List
Featured ProductsSpot supply
Product Name: N-methyl-4-nitrobenzenamine Visit Supplier Webpage Request for quotationCAS: 100-15-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: N-Methyl-4-nitroaniline Request for quotationCAS: 100-15-2
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: N-Methyl-4-nitroaniline Request for quotationCAS: 100-15-2
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: N-Methyl-4-nitroaniline Request for quotationCAS: 100-15-2
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Multiple Specifications
Product Name: N-Methyl-4-nitroaniline Request for quotationCAS: 100-15-2
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: N-Methyl-4-nitroaniline Request for quotationCAS: 100-15-2
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Product Name: N-Methyl-4-nitroaniline Request for quotation
CAS: 100-15-2
Tel: +86 18942506900
Email: lilyqu@chemoway.com
Mobile: +86 18942506900
QQ: 3182628472
Wechat: +86 18942506900
WhatsApp: +86 18942506900
Linkedin: +86 18942506900
CAS: 100-15-2
Tel: +86 18942506900
Email: lilyqu@chemoway.com
Mobile: +86 18942506900
QQ: 3182628472
Wechat: +86 18942506900
WhatsApp: +86 18942506900
Linkedin: +86 18942506900
Spot supply
Product Name: N-methyl-4-nitrobenzenamine Visit Supplier Webpage Request for quotationCAS: 100-15-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: N-Methyl-4-nitroaniline Visit Supplier Webpage Request for quotationCAS: 100-15-2
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Featured ProductsSpot supply
Product Name: N-methyl-4-nitrobenzenamine Visit Supplier Webpage Request for quotationCAS: 100-15-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: N-Methyl-4-nitroaniline Request for quotationCAS: 100-15-2
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: N-Methyl-4-nitroaniline Request for quotationCAS: 100-15-2
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: N-Methyl-4-nitroaniline Request for quotationCAS: 100-15-2
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Multiple Specifications
Product Name: N-Methyl-4-nitroaniline Request for quotationCAS: 100-15-2
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: N-Methyl-4-nitroaniline Request for quotationCAS: 100-15-2
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Product Name: N-Methyl-4-nitroaniline Request for quotation
CAS: 100-15-2
Tel: +86 18942506900
Email: lilyqu@chemoway.com
Mobile: +86 18942506900
QQ: 3182628472
Wechat: +86 18942506900
WhatsApp: +86 18942506900
Linkedin: +86 18942506900
CAS: 100-15-2
Tel: +86 18942506900
Email: lilyqu@chemoway.com
Mobile: +86 18942506900
QQ: 3182628472
Wechat: +86 18942506900
WhatsApp: +86 18942506900
Linkedin: +86 18942506900
Spot supply
Product Name: N-methyl-4-nitrobenzenamine Visit Supplier Webpage Request for quotationCAS: 100-15-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: N-Methyl-4-nitroaniline Visit Supplier Webpage Request for quotationCAS: 100-15-2
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
View History